Michigan State (3-0, 1-0 Big Ten) plays at Boston College (2-1, 1-0 ACC) on Saturday (8 p.m., ACC Network) to kick off a very difficult stretch of the schedule. Here are five things to watch in the game and a final score prediction:

Vanderbilt's Diego Pavia arrived from New Mexico State as a graduate transfer along with his coach, Jerry Kill, and offensive coordinator, Tim Beck. They've provided a big boost to the Commodores’ offense. Pavia mostly relied on his legs in their first two games, but he threw for a season-high 270 yards and two touchdowns last week.

The Missouri Tigers faced their first signs of adversity in their week three matchup with the No. 24 Boston College Eagles. The Tigers found a spark from their defense, leading to a response from the offense. Missouri rallied back thanks to an elusive rushing attack and a breakout freshman kicker.